Perioperative Bleeding Risk Factors



Preoperative Bleeding Risk Factors:
    • Prior bleeding history following surgical procedures
    • Preop coagulopathy
    • Preoperative organ dysfunction
      • Liver disease
      • Kidney disease/renal failure
      • CHF with passive liver congestion
      •  increased LFTs
      •  increased PT
    • History of quantitive or qualitative platelet dysfunction
    • Platelet inhibitors
      • ASA, NSAID
      • GPIIb/IIIa inhibitor
    • Preop anticoagulant use
      • Heparin
      • Warfarin
    • Fibrinolytic administration
      • TPA
      • Streptokinase
      • Urokinase

Intraoperative Course:
    • CPB time (over 150 min increases risk)
    • Administration of blood products
    • Transfusion of “pump blood” or autologous blood (heparinized blood)
    • Administration of antifibrinolytics, DDAVP, or serine protease inhibitor
    • Surgical bleeding sites intraoperative
    • Presence of microvascular bleeding at sternal closure

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