Minimum Alveolar Concentration: dosing

  •  MAC: prevents movement in response to surgical stimulationin 50% of patients
  •  1.3 MAC: prevents movement in response to surgical stimulation in 95% of patients
  • 0.3–0.4 MAC: associated with awakening from anesthesia
  •  1.5–1.7 MAC: the concentration required to block autonomic reflexes to surgical stimulation


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