Anesthesiology and Intensive Care

  V entilation-Perfusion ( V̇/Q̇ ) mismatch is similar to intrapulmonary shunt (V̇/Q̇ = 0) , with some important distinctions.

  Generally, in obese patients, the blood distributes more to nonadipose than to adipose tissues, resulting in higher plasma drug concentrations in obese patients with mg/kg dosing than in normal patients with less adipose mass. ➡

  Anesthesia providers should be familiar with the pharmacologic alterations of anesthetics in obese individuals. In general, manufacturer dosing recommendations are scaled to kilograms of actual total body weight (TBW).➟

Mean Arterial Pressure  (MAP) is the average arterial pressure throughout one cardiac cycle (systole and diastole).  Can be calculated using a Formula: MAP = DP + 1/3(SP - DP)