Anesthesiology and Intensive Care

  Thrombolysis is a medical procedure that involves the use of medication to dissolve blood clots that have formed inside blood vessels. While thrombolysis can be an effective treatment option for certain conditions, there are certain situations where it may not be appropriate due to contraindications.

  Strong Recommendations For patients with PE ( pulmonary embolism ) and hemodynamic compromise, it is recommended that thrombolytic therapy followed by anticoagulation be used over anticoagulation alone. For patients with DVT ( deep vein thrombosis ) and/or PE who have completed primary treatment and will continue vitamin K antagonist (VKA) therapy as secondary prevention, it is recommended that an international normalized ratio (INR) range of 2.0 to 3.0 be used over a lower INR range . For patients with a recurrent unprovoked DVT and/or PE , indefinite antithrombotic therapy is recommended over stopping anticoagulation after completion of primary treatment.