Magnesium & Cardiovascular Diseases
Ischemic Heart Disease Patients with low Mg levels have a higher risk of coronary artery disease. High Mg levels are associated with a reduced cardiovascular disease and mortality. This inverse association between Mg levels and coronary artery disease has been noted both in women and men. Low Mg levels have also been implicated in major adverse events following drug-eluting stent implantation . Mg levels are frequently low after cardiac surgery and may play a role in the development of post-operative arrhythmias. Hypomagnesemia with Mg < 2 mEq/L or less is also associated with increased mortality in ambulatory heart failure patents. The main pathology in ischemic heart disease is atherosclerosis, and Mg deficiency may exacerbate this process. Epidemiological studies have found a direct correlation between low Mg levels and atherosclerosis. Hypomagnesemia also adversely affects lipid metabolism and C-reactive protein. Both of these abnormalities have deleterious eff...