NOBLE: CABG vs.PCI or cabbage seems to be safe)))
WASHINGTON — PCI with a drug-eluting stent was inferior to CABG for the outcome of MACCE at 5 years, according to data presented at TCT 2016 and published in The Lancet . “The study showed that PCI was not noninferior to CABG; in fact, CABG was superior to PCI,” Evald H. Christiansen, MD, PhD , from Aarhus University Hospital in Skejby, Denmark, said in a presentation. The prospective, randomized, open-label, noninferiority NOBLE study was conducted at 36 hospitals in Europe between Dec. 9, 2008 and Jan. 21, 2015. Christiansen and colleagues randomly assigned 1,201 eligible patients with left main CAD to treatment with PCI (n = 598; mean age, 66 years; 20% women) or CABG (n = 603; mean age, 66 years; 24% women). Initially, operators could use any DES on patients assigned PCI, but in March 2010, they were advised to use a biolimus-eluting stent (Biomatrix Flex, Biosensors). Patients were included if they had stable angina pectoris, unst...