Etiologies and diagnosis of fever of unknown origin



Common etiologies of fever of unknown origin:



Infections:
Tuberculosis especially extrapulmonary, abdominal abscess, pelvic abscess, dental abscesses, endocarditis, osteomyelitis, sinusitis, prostatitis, viral (cytomegalovirus, Epstein-Barr, HIV) ricketsial, fungal, malaria, typhoid and kala azar
Malignancies:

Lymphoma, chronic leukemia, metastatic cancer, renal cell carcinoma, colon cancer, hepatoma and sarcomas

Autoimmune conditions:
Adult still’s disease, polymyalgia rheumatica, temporal arteritis, SLE, RA, Reiter’s syndrome, vasculitides and inflammatory bowel disease

Miscellaneous:

Drug-induced fever, factitious fever sarcoidosis, granulomatous hepatitis, DVT and PTE



 Algorithm for the diagnosis of fever of unknown origin:

algorithm of diagnosis of fever of unknown origin

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