Drugs to avoid in Pregnancy.





Drugs known to cause congenital malformations:
  • Anticonvulsants

  • Lithium

  • Cytotoxics
  • Retinoids (systemic)
  • Danazol
  • Warfarin





Drugs that can affect fetal growth and development:


• ACE inhibitors (after 12wks) — fetal or neonatal renal failure;

• Barbiturates, benzodiazepines, and opioids (near term) — drug dependence in fetus;


• NSAIDs (after 12wks) — premature closure of ductus arteriosus;


• Tetracyclines (after 12wks) — abnormalities of teeth and bone;


• Warfarin — fetal or neonatal haemorrhage;

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