The muscarinic antagonists compete with neurally released acetylcholine ( ACh ) for access to muscarinic cholinoceptors and block ACh’s effects. The results are faster heart rate, sedation, and dry mouth. With the exception of the quaternary ammonium compounds that do not readily cross the blood-brain barrier and have few actions on the CNS, there is no significant specificity of action among these drugs; they block all muscarinic effects with equal efficacy, although there are some quantitative differences in effect.