Anticoagulants with the Required Monitoring and Possible Reversal Drugs.

Vitamin K antagonists: 

Drug: Warfarin 

Laboratory tests: PT, INR 

Reversal Agents: Fresh frozen plasma (FFP) and prothrombin complex concentrate (PCC) , vitamin K 

Heparins: 

Drug: Unfractionated heparin (UFH) 

Laboratory tests: activated partial thromboplastin time (aPTT) 

Reversal Agents: Protamine 

Drug: Low-molecular-weight heparin (LMWH) 

Laboratory tests: None required, but anti–factor Xa assay can monitor levels 

Reversal Agents: Partially reversed by protamine.

Pentasaccharide: 

Drug: Fondaparinux 

Laboratory tests: None required, but anti–factor Xa assay can monitor levels 

Reversal Agents: None 

Drug: Dabigatran 

Laboratory tests: None required 

Reversal Agents: Idarucizumab, dialysis may remove drug. 

Factor Xa inhibitors: 

Drug: Rivaroxaban, apixaban 

Laboratory tests: None required 

Reversal Agents: None