Hyperthermia during Cardiopumonary Bypass
Moderate-quality prospective studies have demonstrated that when rewarming on cardiopulmonary bypass (CPB), hyperthermia (core temperature >37.9°C) is associated with cognitive deficits, infection, and renal dysfunction. Any postoperative hyperthermia within 24 hours after coronary artery bypass grafting has been associated with cognitive dysfunction at 4 to 6 weeks. Rewarming on CPB to normothermia should be combined with continuous surface warming. Thus, we recommend avoiding hyperthermia while rewarming on cardiopulmonary bypass (class III, level B-R).
Source: Jama
1.Grocott HP, Mackensen GB, Grigore AM, et al; Neurologic Outcome Research Group (NORG); Cardiothoracic Anesthesiology Research Endeavors (CARE) Investigators’ of the Duke Heart Center. Postoperative hyperthermia is associated with cognitive dysfunction after coronary artery bypass graft surgery. Stroke. 2002;33(2):537-541. doi:10.1161/hs0202.102600PubMedGoogle ScholarCrossref 4.Bar-Yosef S, Mathew JP, Newman MF, Landolfo KP, Grocott HP; Neurological Outcome Research Group; C A R E Investigators of the Duke Heart Center. Prevention of cerebral hyperthermia during cardiac surgery by limiting on-bypass rewarming in combination with post-bypass body surface warming: a feasibility study. Anesth Analg. 2004;99(3):641-646. doi:10.1213/01.ANE.0000130354.90659.63PubMedGoogle ScholarCrossref